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01-Sep-2017 07:45

Most responders (72%) completed the questionnaire via the web; 28% of the responders preferred the telephone interview, of which 12% also completed the paper questionnaire (including the items on ASD and ADHD).Compared with responders, the non-responders more often were male, were less educated and were more often convicted for crime, or diagnosed with a psychiatric disorder.Of this target sample, 25 485 (60%) individuals took part in the Swedish Twin study of Adults: Genes and Environments (STAGE).Twins were sent a letter inviting them to participate in the study and were given a personal login to the study web page, on which they were asked to complete an online questionnaire.In addition, previous studies were underpowered to investigate sex differences in the etiology and associations of ASD and ADHD dimensions.Sex differences are important to consider, as the prevalence of both ASD is higher in males than in females.Non-responders were approached with up to three reminders.

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The few studies in adults showed similar results with genetic correlations between ASD and ADHD traits of ~0.60.

ASDr showed the strongest associations with IA and HI in both sexes (r 0.20).

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